President Donald Trump addressed the nation on Thursday night to announce the launch of TrumpRx.gov featuring medicine at discount prices.

“This launch represents the largest reduction in prescription drug prices in history by many, many times,” Trump said.

The president said Americans no longer subsidize drug costs for the rest of the world.

“It’s not going to happen any longer,” Trump said. “We ended it.”

His administration negotiated most-favored-nation status with drug manufacturers and other nations, lowering costs of some medicines by 80 percent or more, according to the president.

“This is a very big deal,” Trump said. We’re going to save a lot of money and be healthy.”

More than 40 drugs are now available on the website at discounted prices. Fertility treatments, asthma medicines, and many more products are listed by various manufacturers.

The site operates as a search function, connecting patients with valid prescriptions with coupons redeemable at local pharmacies.

Prices for the Bevespi Aerosphere inhaler will decline from $458 to $51, according to a White House statement.

Obesity medications Ozempic and Wegovy are available for an approximate price of $350, compared to $1,028 and $1,349, respectively. Wegovy pills will sell for $149 instead of $1,349.

Administration officials touted opportunities for cost savings nationwide.

“This historic announcement will save millions of Americans their hard-earned money,” White House press secretary Karoline Leavitt said during a Feb. 5 briefing.

The administrator for the Centers for Medicaid and Medicare Services, Dr. Mehmet Oz, and National Design Studio Director Joe Gebbia accompanied the president for the prime-time address.

“Today, you can now get access to these steeply discounted prices,” Oz said during the ceremony. “You should not be buying drugs anymore, going forward, without checking to see if those drugs are available on TrumpRx.gov.”

The doctor said access to fertility drugs, including Gonal-F, at lower prices will spur a surge in births, dubbing them “Trump babies.”

A military spouse already benefiting from the program thanked Trump and his administration for reducing barriers to fertility treatments.

“The president’s leadership ... has a real and immediate impact,” said Catherine Rayner. “For families like ours, it can mean the difference between being able to continue treatment or having no choice but to stop.”

Administration officials estimate savings of approximately $2,000 per cycle for fertility medicines.

Gebbia, who oversaw site development, said administrators prioritized high-priced medicines with cost savings potential, with more medicines coming soon.

Trump first announced the website, which allows consumers to purchase some pharmaceutical drugs directly from manufacturers, such as Pfizer and Amgen, among others, on Sept. 30.

Eliminating middlemen, including pharmacy benefit managers, reduces costs, officials said. Insured and uninsured Americans are expected to benefit from no prior authorizations and lower prices.

Patients across the country spent more than $805 billion on prescription drugs in 2024, according to the latest data available from the National Institutes of Health.

During a press conference on the one-year anniversary of his second term, the president highlighted efforts to lower drug prices as one of his key achievements.

“I think that most favored nations for drugs is something that nobody thought they’d be able to get,” Trump said.

“Tariffs helped me there because the nations would have never gone along with it if I wasn’t able to say, ‘If you don’t go along with it, we’re going to put a 10 or 15 or 20 percent tariff on your nation.’ And they went along, and our drug prices are going to come down at numbers never even seen before, never even thought possible before.”

Correction: A previous version of this article misstated the url for the new website. The Epoch Times regrets the error.