Harvard researchers tracked tens of thousands of people for decades and found a fascinating pattern: There’s one specific mindset trait that made people up to 70 percent more likely to reach age 85.

This powerful mindset is optimism, and it physically alters your cells, your heart, and your immune response. Even more surprising is the factor that matters three times more than optimism itself.

In this video, we break down the biology of how you interpret setbacks, what happens in your body when you face adversity, and a simple mindset shift that changes how you experience failure.